CHEMOTHERAPY VERSUS BEST SUPPORTIVE CARE IN
ANELLI A et al.Chemotherapy versus best supportive care in stage IV non-small cell lung cancer non metastatic to the brain. Rev. Hosp. Clín. Fac. Med. S. Paulo 56(2) 53-58 2001. Stage IV non-small cell lung cancer is a fatal disease with a median survival of 14 months. Systemic chemotherapy is the most common approach.
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Second-line chemotherapy versus supportive cancer
Nov 01 2013 · Overall survival was compared for 238 patients who were assigned to irinotecan or docetaxel as salvage chemotherapy with 172 patients who received supportive care. A significant reduction in the risk of death (HR = 0.64 95 CI 0.52–0.79 P < 0.0001) was observed with salvage chemotherapy as shown in Figure 2. Heterogeneity was not detected.
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Chemotherapy vs supportive care alone for relapsed gastric
chemotherapy compared with active symptom control or best supportive care (SC) alone hereafter referred to as SC (Thuss-Patience et al 2011 Kang et al 2012 Ford et al 2014). A further phase 3 trial compared paclitaxel and irinotecan chemotherapy without a SC arm and described similar OS for both chemotherapies (Hironaka et al 2013).
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Comparison of salvage chemoradiation versus salvage
Feb 01 2014 · Read "Comparison of salvage chemoradiation versus salvage surgery for recurrent esophageal squamous cell carcinoma after definitive radiochemotherapy or radiotherapy alone Diseases of the Esophagus" on DeepDyve the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
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Vinorelbine Ifosfamide and Cisplatin Combination as
Background Platinum-based chemotherapy improves survival and quality of life as compared with the best supportive care alone in advanced non-small cell lung cancer. In addition several recent studies using new drugs such as docetaxel have demonstrated that second-line chemotherapy may be of value.
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Active salvage chemotherapy versus best supportive care
Active salvage chemotherapy versus best supportive care for patients with recurrent or metastatic squamous cell carcinoma of the esophagus refractory or intolerable to fluorouracil platinum and taxane. Nomura M(1)(2) Iwasa S(3) Tsushima T(4) Kato K(3) Yasui H(4) Boku N(3) Muto M(5) Muro K(6).
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CHEMOTHERAPY VERSUS BEST SUPPORTIVE CARE IN
ANELLI A et al.Chemotherapy versus best supportive care in stage IV non-small cell lung cancer non metastatic to the brain. Rev. Hosp. Clín. Fac. Med. S. Paulo 56(2) 53-58 2001. Stage IV non-small cell lung cancer is a fatal disease with a median survival of 14 months. Systemic chemotherapy is the most common approach.
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Salvage Therapy in Advanced Adult Soft Tissue Sarcoma A
Finally RR with new agents or chemotherapy doublets translated from 4.3 to 7.6 (OR = 1.78 95 CI 1.22–2.50). Conclusion. Better survival is achieved in patients treated with salvage therapies (chemotherapy as single or multiple agents or targeted biological agents). A 3‐months gain in OS and an almost double RR is observed.
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REFERENCESEvidence-Based Clinical Decision Support at
Kang JH Lee SI Lim DH et al. Salvage chemotherapy for pretreated gastric cancer a randomized phase III trial comparing chemotherapy plus best supportive care with best supportive care alone. J Clin Oncol 2012 30 1513.
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Chemotherapy vs supportive care alone for relapsed gastric
chemotherapy compared with active symptom control or best supportive care (SC) alone hereafter referred to as SC (Thuss-Patience et al 2011 Kang et al 2012 Ford et al 2014). A further phase 3 trial compared paclitaxel and irinotecan chemotherapy without a SC arm and described similar OS for both chemotherapies (Hironaka et al 2013).
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Active salvage chemotherapy versus best supportive care
Oct 24 2016 · Active salvage chemotherapy versus best supportive care for patients with recurrent or metastatic squamous cell carcinoma of the esophagus refractory or intolerable to fluorouracil platinum and taxane. Motoo Nomura 1 2
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Radioembolization for Treatment of Salvage Patients with
Matched-pair comparison of radioembolization plus best supportive care versus best supportive care alone for chemotherapy refractory liver-dominant colorectal metastases. Cardiovasc Intervent Radiol. 2012 35 .
Get PriceSalvage chemotherapy in gastric cancer—more than a straw
A randomized multicentre study has shown that irinotecan or docetaxel administered as single agents improved survival compared with best supportive care alone. Hence salvage chemotherapy is now a
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Radioembolization for Treatment of Salvage Patients with
Matched-pair comparison of radioembolization plus best supportive care versus best supportive care alone for chemotherapy refractory liver-dominant colorectal metastases. Cardiovasc Intervent Radiol. 2012 35 .
Get PriceCHEMOTHERAPY VERSUS BEST SUPPORTIVE CARE IN
ANELLI A et al.Chemotherapy versus best supportive care in stage IV non-small cell lung cancer non metastatic to the brain. Rev. Hosp. Clín. Fac. Med. S. Paulo 56(2) 53-58 2001. Stage IV non-small cell lung cancer is a fatal disease with a median survival of 14 months. Systemic chemotherapy is the most common approach.
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Radioembolization versus Standard Care of Hepatic
Jan 01 2012 · The present study suggests that radioembolization shows promise as an effective and safe treatment for patients with chemotherapy-refractory hepatic metastases and improves overall survival in a select population of patients in a salvage setting compared with best supportive care alone.
Get PriceGuidelines Consider Use of Targeted Therapies in
Van Cutsem E Peeters M Siena S et al. Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy- refractory metastatic colorectal cancer. J Clin Oncol. 200725(13) . doi 10.1200/JCO.2006.08.1620. Tabernero J Yoshino T Cohn AL.
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Gastric Cancer Chemotherapy for Advanced Disease with
Kang JH Lee SI Lim DH Park KW Oh SY et al. Salvage chemotherapy for pretreated gastric cancer a randomized phase III trial comparing chemotherapy plus best supportive care with best supportive care alone. J Clin Oncol. 201230 1513–8. CrossRef Google Scholar
Get PriceWhich treatments work best for advanced stomach cancer
Chemotherapy versus placebo best supportive care or no treatment Chemotherapy probably improves OS (HR = 0.66 95 CI 0.52 to 0.83 moderate-certainty evidence) based on two studies involving 547 participants and improves PFS (HR = 0.57 95 CI 0.47 to 0.69 high-certainty evidence) based on one study involving 507 participants over placebo
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The efficacy and safety comparison of PD-1/PD-L1 antibody
Kang JH Lee SI Lim DH et al. Salvage chemotherapy for pretreated gastric cancer a randomized phase III trial comparing chemotherapy plus best supportive care with best supportive care alone. J Clin Oncol 201230 1513-8.
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Gastric Cancer Chemotherapy for Advanced Disease with
Kang JH Lee SI Lim DH Park KW Oh SY et al. Salvage chemotherapy for pretreated gastric cancer a randomized phase III trial comparing chemotherapy plus best supportive care with best supportive care alone. J Clin Oncol. 201230 1513–8. CrossRef Google Scholar
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Advances in target therapy in lung cancer European
As salvage therapy they have been compared to best supportive care or chemotherapy or tested after the first TKI failed. Finally some trials have tested intercalated TKIs with chemotherapy. Recently published RCTs in unselected populations have dealt with salvage
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(PDF) Secondline Chemotherapy Versus Best Supportive Care
The role of second-line and salvage chemotherapy in malignant pleural mesothelioma treatment is not yet established. data from a randomized trial vs. best supportive care suggest the use of
Get Price(PDF) Secondline Chemotherapy Versus Best Supportive Care
The role of second-line and salvage chemotherapy in malignant pleural mesothelioma treatment is not yet established. data from a randomized trial vs. best supportive care suggest the use of
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Retrospective observational study of salvage line
Apr 21 2020 · Ramucirumab monotherapy as a second-line treatment for advanced gastric cancer (AGC) prolongs survival compared to the best supportive care. However in clinical practice ramucirumab monotherapy is sometimes used as third- or later-line treatment for AGC refractory to fluoropyrimidine and taxanes. This study evaluated the efficacy and safety of salvage-line
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May 20 2015 · Salvage chemotherapy versus best supportive care in patients with recurrent or metastatic squamous cell carcinoma of the esophagus refractory or intolerable to
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Comparison of salvage chemoradiation versus salvage
Mar 01 2014 · Thirty-six patients underwent salvage CRT consisting of two cycles of chemotherapy concurrent with intensity-modulated radiation therapy (IMRT) and the chemotherapy regimen was as follows paclitaxel 135 mg/m 2 infusion for 3 hours on day 1 cisplatin 25 mg/ m 2 infusion on days 1 to 3 repeated every 3 weeks. IMRT was administered to a total
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Salvage Therapy for Advanced Non‐Small Cell Lung Cancer
Treatment guidelines recommend platinum‐based chemotherapy first line for patients with a good performance status. These regimens offer a modest survival advantage over best supportive care. The role of targeted biologic agents in this setting is being assessed in phase II trials. Results to date show promising activity and tolerability.
Get PriceGuidelines Consider Use of Targeted Therapies in
Van Cutsem E Peeters M Siena S et al. Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy- refractory metastatic colorectal cancer. J Clin Oncol. 200725(13) . doi 10.1200/JCO.2006.08.1620. Tabernero J Yoshino T Cohn AL.
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